E-3620

E-3620 is a potent 5-HT3 receptor antagonist. E-3620 can be used for the research of dyskinesi and gastrointestinal motility[1][2].

Product Specifications

CAS Number

[151213-86-4]

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/e-3620.html

Concentration

10mM

Purity

98.88

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H]1C[C@@H](N2C)CC[C@@H]2C1)C3=CC(Cl)=C(N)C=C3O[C@@H](C)C#CC.[H]Cl

Molecular Formula

C20H27Cl2N3O2

Molecular Weight

412.35

References & Citations

[1]George Peter Arthur Rice. 5-ht3 receptor antagonists for dyskinesia. CA2231887A1.|[2]Edwin Bernard Villhauer, et al. Combination of dipeptidyl peptidase IV (DPP-IV) inhibitors and compounds modulating 5-HT3 and/or 5-HT4 receptors for therapeutic use. WO2006005613A1.