CIAP1 Ligand-Linker Conjugates 15
CIAP1 Ligand-Linker Conjugates 15 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 15 can be used to design SNIPERs[1].
Product Specifications
CAS Number
1225433-96-4
Product Name Alternative
E3 ligase Ligand-Linker Conjugates 34
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugates-34.html
Solubility
10 mM in DMSO
Smiles
NCCOCCOCCOC([C@H](CC(C)C)NC([C@@H](O)[C@@H](CC1=CC=CC=C1)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=O)=O
Molecular Formula
C37H47N3O8
Molecular Weight
661.78
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Itoh Y, et al. Protein knockdown using methyl bestatin-ligand hybrid molecules: design and synthesis of inducers of ubiquitination-mediated degradation of cellular retinoic acid-binding proteins. J Am Chem Soc. 2010 Apr 28;132 (16) :5820-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CIAP1
Available Sizes
Frequently Asked Questions
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