Azidoethyl-SS-ethylamine
Product Specifications
UNSPSC Description
Azidoethyl-SS-ethylamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azidoethyl-SS-ethylamine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/azidoethyl-ss-ethylamine.html
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
NCCSSCCN=[N+]=[N-]
Molecular Weight
178.28
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-140104/Azidoethyl-SS-ethylamine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-140104/Azidoethyl-SS-ethylamine-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1807512-40-8
Available Sizes
Curated Selection
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