LCAHA
LCAHA (LCA hydroxyamide) is a deubiquitinase USP2a inhibitor with IC50s of 9.7 μM and 3.7μM in Ub-AMC Assay and Di-Ub Assay, respectively. LCAHA destabilizes Cyclin D1 and induces G0/G1 arrest by inhibiting deubiquitinase USP2a[1].
Product Specifications
CAS Number
117094-40-3
Product Name Alternative
LCA hydroxyamide
UNSPSC
12352211
Hazard Statement
H302, H312, H332
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lcaha.html
Purity
99.91
Solubility
DMSO : 45 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NO)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])CC3)C
Molecular Formula
C24H41NO3
Molecular Weight
391.59
Precautions
H302, H312, H332
References & Citations
01
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940636-100 1x 100 µL
Human Lambda Light Chain (LAM03), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details ![CTLA4 Mouse Monoclonal Antibody [Clone ID: OTI9F3]](https://cdn.genprice.uk/products/937/68dd18bb061270361e908f0e/imageurl/cf813260.webp)