Fmoc-GGFG-DXd
Fmoc-GGFG-DXd is a drug-linker conjugate for ADC. Fmoc-GGFG-DXd contains a ADC linker Fmoc-GGFG and a DNA topoisomerase I inhibitor DXd (HY-13631D) [1].
Product Specifications
CAS Number
[1599440-11-5]
UNSPSC
12352203
Hazard Statement
H301
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-ggfg-dxd.html
Purity
99.81
Solubility
DMSO : 175 mg/mL (ultrasonic)
Smiles
O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)NCC(NCC(N[C@@H](CC4=CC=CC=C4)C(NCC(NCOCC(N[C@@H]5C6=C7C(C(N8C7)=CC([C@](O)(C(OC9)=O)CC)=C9C8=O)=NC%10=CC(F)=C(C)C(CC5)=C%106)=O)=O)=O)=O)=O
Molecular Formula
C57H55FN8O12
Molecular Weight
1063.09
Precautions
H301
References & Citations
[1]Lingpei Kong, et al. Synthetic method for antibody-conjugated drug linker LND1067. CN113336823A.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Traditional Cytotoxic Agents
Available Sizes
Curated Selection
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