Amoscanate

Amoscanate (cgp4540) is phenyl isothiocyanate in which the hydrogen at the para-position has been replaced by a 4-nitroanilinyl group. Amoscanate is an anti-schistosomal agent. Amoscanate, as an isothiocyanate compound and uncoupler of oxidative phosphorylation, potently injures rodent ependyma[1].

Product Specifications

CAS Number

[26328-53-0]

Product Name Alternative

CGP4540

UNSPSC

12352005

Hazard Statement

H301, H315, H319, H334, H335

Target

Oxidative Phosphorylation; Parasite

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/amoscanate.html

Purity

99.45

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=[N+]([O-])C(C=C1)=CC=C1NC2=CC=C(C=C2)N=C=S

Molecular Formula

C13H9N3O2S

Molecular Weight

271.29

Precautions

H301, H315, H319, H334, H335

References & Citations

[1] Johanson C, et al. The distributional nexus of choroid plexus to cerebrospinal fluid, ependyma and brain: toxicologic/pathologic phenomena, periventricular destabilization, and lesion spread. Toxicol Pathol. 2011;39 (1) :186-212.