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Alteminostat

Alteminostat (CKD-581) is a potent HDAC inhibitor. Alteminostat inhibits the class I-II HDAC family via histone H3 and tubulin acetylation. Alteminostat can be used for lymphoma and multiple myeloma research[1].

Product Specifications

Product Name Alternative

CKD-581

UNSPSC

12352005

Target

Apoptosis; HDAC

Type

Reference compound

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/alteminostat.html

Concentration

10mM

Purity

98.66

Solubility

DMSO : 230 mg/mL (ultrasonic)

Smiles

O=C(N1CCN(C)CC1)N(CCCCCCC(NO)=O)C2=CC=C(C3=CC4=C(C=C3)C=NN4C)C=C2

Molecular Formula

C27H36N6O3

Molecular Weight

492.61

References & Citations

[1]Soo Jin Kim, et al. Anti-Cancer Effects of CKD-581, a Potent Histone Deacetylase Inhibitor against Diffuse Large B-Cell Lymphoma. Int J Mol Sci. 2020 Jun 19;21 (12) :4377.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-109109/Alteminostat-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-109109/Alteminostat-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

Phase 1

CAS Number

[1246374-97-9]

Available Sizes

Curated Selection

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