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Diacetoxy-6-gingerdiol

Diacetoxy-6-gingerdiol is a gingerol isolated with anti-inflammatory and antioxidant effects, which is found in the dichloromethane extract of rhizomes of ginger (Zingiber officinale Roscoe) . Diacetoxy-6-gingerdiol protects the extracellular matrix of nucleus pulposus cells and ameliorates intervertebral disc degeneration by inhibiting the IL-1β-mediated NLRP3 pathway[1][2][3].

Product Specifications

CAS Number

143615-75-2

UNSPSC

12352005

Target

Interleukin Related

Type

Natural Products

Related Pathways

Immunology/Inflammation

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/diacetoxy-6-gingerdiol.html

Purity

98.01

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

CCCCC[C@H](OC(C)=O)C[C@H](OC(C)=O)CCC1=CC=C(O)C(OC)=C1

Molecular Formula

C21H32O6

Molecular Weight

380.48

References & Citations

[1]HiroeKikuzaki, et al. Gingerdiol related compounds from the rhizomes of Zingiber officinale. Phytochemistry. Volume 31, Issue 5, 1 May 1992, Pages 1783-1786.|[2]Xi H, et al. Diacetoxy-6-gingerdiol protects the extracellular matrix of nucleus pulposus cells and ameliorates intervertebral disc degeneration by inhibiting the IL-1β-mediated NLRP3 pathway. Heliyon. 2024 Sep 18;10 (21) :e37877.|[3]Asamenew G, et al. Characterization of phenolic compounds from normal ginger (Zingiber officinale Rosc.) and black ginger (Kaempferia parviflora Wall.) using UPLC–DAD–QToF–MS[J]. European Food Research and Technology, 2019, 245: 653-665.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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