Ganglioside GD3 (diammonium)
Product Specifications
UNSPSC Description
Ganglioside GD3 diammonium is an acidic glycosphingolipid. Ganglioside GD3 diammonium inhibits the proliferation of cancer cells, affects the opening of the mitochondrial permeability transition pore (PTPC), induces apoptosis and activates caspase family. Ganglioside GD3 diammonium can be used in research about cancer and neurodegenerative diseases[1].
Target Antigen
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ganglioside-gd3-diammonium.html
Purity
98.0
Smiles
OC([C@](O[C@@]([C@@H]1NC(C)=O)([H])[C@H](O)[C@@H](CO)O[C@@](O[C@@]([C@@H]2NC(C)=O)([H])[C@H](O)[C@H](O)CO)(C[C@@H]2O)C(O)=O)(C[C@@H]1O)O[C@@H]([C@H]([C@H]3CO)O)[C@H]([C@@H](O3)O[C@@H]([C@@H]([C@H]4O)O)[C@H](O[C@H]4OC[C@@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCCCCCCCCCCCCCC)=O)CO)O)=O.N.N
Molecular Weight
1506.81
References & Citations
[1]Malisan F, et al., GD3 ganglioside and apoptosis. Biochim Biophys Acta. 2002 Dec 30;1585(2-3):179-87.|[2]Kazunori Hamamura, et al. Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11041-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-131139A/Ganglioside-GD3-diammonium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-131139A/Ganglioside-GD3-diammonium-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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