TBAJ-587
TBAJ-587, a potent anti-tuberculosis agent, inhibits M.tb strain H37Rv growth with MIC90s of 0.006 and [1].
Product Specifications
CAS Number
[2252316-16-6]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/TBAJ-587.html
Purity
99.69
Solubility
DMSO : 43.33 mg/mL (ultrasonic)
Smiles
COC1=C(F)C([C@H](C2=CC3=CC(Br)=CC=C3N=C2OC)[C@](O)(C4=CC(OC)=NC(OC)=C4)CCN(C)C)=CC=C1
Molecular Formula
C30H33BrFN3O5
Molecular Weight
614.50
References & Citations
[1]Sutherland HS, et al. 3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel. Bioorg Med Chem. 2019 Apr 1;27 (7) :1292-1307.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Curated Selection
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