1-Stearoyl-sn-glycero-3-phosphocholine
1-Stearoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine that inhibits HDAC3 activity and phosphorylation of STAT3 in K562 cells. 1-Stearoyl-sn-glycero-3-phosphocholine induces apoptosis and exhibits anticancer activity in chronic myelogenous leukemia (CML) K562 cells[1].
Product Specifications
CAS Number
19420-57-6
Product Name Alternative
18:0 Lyso-PC; LPC (18:0)
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Endogenous Metabolite; HDAC; STAT
Type
Biochemical Assay Reagents
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics; JAK/STAT Signaling; Metabolic Enzyme/Protease; Stem Cell/Wnt
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/1-stearoyl-sn-glycero-3-phosphocholine.html
Purity
99.53
Solubility
Ethanol : 12.5 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic)
Smiles
CCCCCCCCCCCCCCCCCC(OC[C@@H](O)COP(OCC[N+](C)(C)C)([O-])=O)=O
Molecular Formula
C26H54NO7P
Molecular Weight
523.68
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Isoform
HDAC3; STAT3
Available Sizes
Frequently Asked Questions
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