α-Tocopherol (phosphate)

α-Tocopherol phosphate is an antioxidant that protects against long-wave UVA1 induced cell death and scavenge UVA1 induced ROS in a skin cell model. α-Tocopherol phosphate exhibits angiogenesis-promoting activity[1][2].

Product Specifications

CAS Number

[38976-17-9]

Product Name Alternative

Alpha-Tocopherol phosphate; TocP; vitamin E phosphate

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Apoptosis; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/_alpha_-tocopherol-phosphate.html

Purity

98.0

Solubility

DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL

Smiles

CC1=C(O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CC2)C2=C(C)C(OP(O)(O)=O)=C1C

Molecular Formula

C29H51O5P

Molecular Weight

510.69

Precautions

H315, H319

References & Citations

[1]Wu Z, Zheng X, Meng L, et al. α-Tocopherol, especially α-tocopherol phosphate, exerts antiapoptotic and angiogenic effects on rat bone marrow-derived endothelial progenitor cells under high-glucose and hypoxia conditions. J Vasc Surg. 2018;67 (4) :1263-1273|[2]Saleh MM, et al. The photoprotective properties of α-tocopherol phosphate against long-wave UVA1 (385 nm) radiation in keratinocytes in vitro. Sci Rep. 2021 Nov 17;11 (1) :22400.