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AF/LE Purified Anti-Mouse CD11c Antibody[N418]

Product Specifications

Background

CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18) . It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.

Abbreviation

CD11c

Gene ID

16411

UniProt

Q9QXH4

Host

Armenian Hamster

Reactivity

Mouse

Immunogen

Recombinant Mouse CD11c protein

Target

Leukocyte adhesion receptor p150+; CD11 antigen-like family member C; CD11c; Integrin alpha-X; Leukocyte adhesion receptor p150+95; Itgax; p150-95; CR4; integrin &alpha-X-X

Clonality

Monoclonal

Clone

N418

Conjugation

None (AF/LE)

Applications

FCM

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Isotype

Armenian Hamster IgG

Available Sizes

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