FAK inhibitor 7
Selected Variant
HY-162879
Size: 1 Each
FAK inhibitor 7 is a type of FAK inhibitor with an IC50 value of 3.58 nM. FAK inhibitor 7 can inhibit the downstream signaling cascades of FAK (like Src and AKT), causing ovarian cancer cells to stall in the G0/G1 phase and induce cytotoxic autophagy. FAK inhibitor 7 can also suppress tumor metastasis and growth in ovarian cancer mice[1].
Product Specifications
CAS Number
2890814-94-3
UNSPSC
12352211
Target
Akt; Autophagy; FAK; Src
Type
Reference compound
Related Pathways
Autophagy; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fak-inhibitor-7.html
Smiles
O=C1CCC2=C1C(OC3=C4C(NC=C4)=NC(NC5=CC=C(N6CCC(N7CCN(C)CC7)CC6)C=C5OC)=N3)=CC=C2
Molecular Formula
C32H37N7O3
Molecular Weight
567.68
References & Citations
[1]Feng Z, et al. A novel selective FAK inhibitor E2 inhibits ovarian cancer metastasis and growth by inducing cytotoxic autophagy. Biochem Pharmacol. 2024 Aug 3;229:116461.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Price
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