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FAK inhibitor 7

Selected Variant

HY-162879

Size: 1 Each

FAK inhibitor 7 is a type of FAK inhibitor with an IC50 value of 3.58 nM. FAK inhibitor 7 can inhibit the downstream signaling cascades of FAK (like Src and AKT), causing ovarian cancer cells to stall in the G0/G1 phase and induce cytotoxic autophagy. FAK inhibitor 7 can also suppress tumor metastasis and growth in ovarian cancer mice[1].

Product Specifications

CAS Number

2890814-94-3

UNSPSC

12352211

Target

Akt; Autophagy; FAK; Src

Type

Reference compound

Related Pathways

Autophagy; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fak-inhibitor-7.html

Smiles

O=C1CCC2=C1C(OC3=C4C(NC=C4)=NC(NC5=CC=C(N6CCC(N7CCN(C)CC7)CC6)C=C5OC)=N3)=CC=C2

Molecular Formula

C32H37N7O3

Molecular Weight

567.68

References & Citations

[1]Feng Z, et al. A novel selective FAK inhibitor E2 inhibits ovarian cancer metastasis and growth by inducing cytotoxic autophagy. Biochem Pharmacol. 2024 Aug 3;229:116461.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Price

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