PRX-07034 (hydrochloride)
PRX-07034 hydrochloride is a highly selective and potent 5-HT6 receptor antagonist with a Ki= 4-8 nM and an IC50 of 19 nM. PRX-07034 can be used for the research of enhancing working memory and cognitive flexibility[1].
Product Specifications
CAS Number
[903580-39-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/prx-07034-hydrochloride.html
Purity
98.97
Solubility
DMSO : 31.25 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 4.76 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C(N2CCNCC2)C=C1NC(C)C3=CC(Cl)=CC(OC)=C3OC)(C)=O.[H]Cl
Molecular Formula
C21H29Cl2N3O4S
Molecular Weight
490.44
Precautions
H302, H315, H319
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
5-HT6 Receptor; mLAG-3; MUC2; α-1 microglobulin
Available Sizes
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