Trevogrumab
Product Specifications
UNSPSC Description
Trevogrumab (REGN-1033) is a monoclonal antibody targeting GDF8 (growth differentiation factor 8, also known as muscle growth inhibitor). Trevogrumab is used in studies of sarcopenia, including wasting atrophy, chronic diseases, and changes in food and nutritional intake[1].
Target Antigen
TGF-beta/Smad
Type
Inhibitory Antibodies
Related Pathways
Stem Cell/Wnt;TGF-beta/Smad
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/trevogrumab.html
Purity
98.86
Solubility
10 mM in DMSO
Smiles
[Trevogrumab]
References & Citations
[1]Masakazu Saitoh, et al. Myostatin inhibitors as pharmacological treatment for muscle wasting and muscular dystrophy. Volume2, Issue1,January 2017,Pages 1-10
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P99388/Trevogrumab-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P99388/Trevogrumab-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
1429201-24-0
Available Sizes
Curated Selection
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