Concanavalin A

Concanavalin A is a Ca2+/Mn2+-dependent and mannose/glucose-binding plant lectin that can be found in jack bean. Concanavalin A can induce programmed cell death. Concanavalin A can be used to induce acute hepatic injury[1][3].

Product Specifications

CAS Number

[11028-71-0]

UNSPSC

12352200

Hazard Statement

H317, H334, H361

Target

Antibiotic; Apoptosis

Type

Biochemical Assay Reagents

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/concanavalin-a.html

Purity

Solubility

H2O : 8.33 mg/mL (ultrasonic)

Smiles

[ConcanavalinA]

Precautions

H317, H334, H361

References & Citations

[1]Li W, et, al. Concanavalin A: a potential anti-neoplastic agent targeting apoptosis, autophagy and anti-angiogenesis for cancer therapeutics. Biochem Biophys Res Commun. 2011 Oct 22;414 (2) :282-6. |[2]Cantelli A, et, al. Concanavalin A-Rose Bengal bioconjugate for targeted Gram-negative antimicrobial photodynamic therapy. J Photochem Photobiol B. 2020 Mar 13;206:111852. |[3]Zhou Y, et al. The Protective Effect of Resveratrol on Concanavalin-A-Induced Acute Hepatic Injury in Mice. Gastroenterol Res Pract. 2015;2015:506390.