Quinoline-2-carboxylic acid-d6
Quinoline-2-carboxylic acid-d6 is the deuterium labeled Quinoline-2-carboxylic acid. Quinoline-2-carboxylic acid exhibits antidiabetic activity. Quinoline-2-carboxylic acid can be used as drug intermediate for synthesis of various active compounds[1][2].
Product Specifications
CAS Number
1219802-18-2
UNSPSC
12352005
Target
Amylases; Glycosidase; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Solubility
10 mM in DMSO
Smiles
OC(C1=NC2=C(C([2H])=C([2H])C([2H])=C2[2H])C([2H])=C1[2H])=O
Molecular Formula
C10HD6NO2
Molecular Weight
179.21
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Lee H W, et al., Quinoline-2-carboxylic acid isolated from Ephedra pachyclada and its structural derivatives show inhibitory effects against α-glucosidase and α-amylase[J]. Journal of the Korean Society for Applied Biological Chemistry, 2014, 57: 441-444.|[3]Yang R, et al., Synthesis of Quinoline-2-Carboxylic Acid Aryl Ester and Its Apoptotic Action on PC3 Prostate Cancer Cell Line. Appl Biochem Biotechnol. 2023 Aug;195 (8) :4818-4831.|[4]Wade JJ, et al., Antiallergic activity of tetracyclic derivatives of quinoline-2-carboxylic acid. 2. Some benzothienoquinolinecarboxylic acids. J Med Chem. 1978 Sep;21 (9) :941-8.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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