Anastrozole
Anastrozole is a potent, highly selective aromatase inhibitor, which inhibits human placental aromatase with an IC50 of 15 nM.
Product Specifications
CAS Number
120511-73-1
Product Name Alternative
ZD1033
UNSPSC
12352005
Hazard Statement
H302, H360
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Anastrozole.html
Purity
99.95
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CC(C)(C#N)C1=CC(C(C)(C#N)C)=CC(CN2C=NC=N2)=C1
Molecular Formula
C17H19N5
Molecular Weight
293.37
Precautions
H302, H360
References & Citations
[1]Dukes M, et al. The preclinical pharmacology of "Arimidex" (anastrozole; ZD1033) --a potent, selective aromatase inhibitor. J Steroid Biochem Mol Biol. 1996 Jul;58 (4) :439-45.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Aromatase/CYP19A1
Available Sizes
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