Enpp-1-IN-16
Enpp-1-IN-16 (compound 54) is an ENPP1 inhibitor. Enpp-1-IN-16 has the potential to study cancer, especially in cases of high ENPP1 expression or elevated cytoplasmic DNA levels. Enpp-1-IN-16 can also be used in other diseases mediated by ENPP1, such as bacterial or viral infections, insulin resistance and type II diabetes, chondrocalcinosis and osteoarthritis, calcium pyrophosphate deposition disorder (CPPD), low Phosphatase disease and soft tissue calcification disorders[1].
Product Specifications
CAS Number
[2289739-47-3]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/enpp-1-in-16.html
Purity
98.46
Solubility
DMSO : 2 mg/mL (ultrasonic)
Smiles
O=C(N1CCC2(CCN(CC2)C3=C4C=C(OC)C(OC)=CC4=NC=N3)C1)OC(C)(C)C
Molecular Formula
C23H32N4O4
Molecular Weight
428.52
References & Citations
[1]Derek A Cogan, et al. Imino sulfanone inhibitors of enpp1. WO2021225969A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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