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CE112 rabbit pAb

This gene encodes a coiled-coil domain containing protein that belongs to the cell division control protein 42 effector protein family. In neurons, it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression. In addition, the protein has been identified as a component of the human centrosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014],

Product Specifications

Background

This gene encodes a coiled-coil domain containing protein that belongs to the cell division control protein 42 effector protein family. In neurons, it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression. In addition, the protein has been identified as a component of the human centrosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Product Name Alternative

Centrosomal protein of 112 kDa (Coiled-coil domain-containing protein 46)

UniProt

Q8N8E3

Swiss Prot

Q8N8E3

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human CE112 AA range: 475-525

Target

CE112

Clonality

Polyclonal

Source

Rabbit

Applications

WB

Concentration

1 mg/ml

Dilution

WB 1:500-2000

Buffer

-20°C/1 year

Molecular Weight

105kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

105kD

Fragment

IgG

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Localizes around spindle poles in some cells. .

Other Product Names

Centrosomal protein of 112 kDa (Coiled-coil domain-containing protein 46)

Gene ID (Human)

201134

Available Sizes

Curated Selection

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