Aconine
Aconine inhibits receptor activator of nuclear factor (NF) -κB ligand (RANKL) -induced NF-κB activation.
Product Specifications
CAS Number
509-20-6
Product Name Alternative
Jesaconine
UNSPSC
12352005
Hazard Statement
H300+H330
Target
NF-κB
Type
Natural Products
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/Aconine.html
Purity
99.81
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@H]1C[C@H](OC)[C@@]23[C@]([H])(C4)[C@]5([H])[C@@H](O)[C@@]4(O)[C@@H](OC)[C@H](O)[C@]5(O)[C@H]6[C@H](OC)[C@@]([H])2[C@]1(COC)CN(CC)[C@H]63
Molecular Formula
C25H41NO9
Molecular Weight
499.59
Precautions
H300+H330
References & Citations
[1]Zeng XZ, et al. Aconine inhibits RANKL-induced osteoclast differentiation in RAW264.7 cells by suppressing NF-κB and NFATc1 activation and DC-STAMP expression. Acta Pharmacol Sin. 2016 Feb;37 (2) :255-63.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
NF-κB
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC423406 20 µg
ZNF407-AS1 (NM_001008234) Human Over-expression Lysate
Sign In for Pricing
View Details 
BNUB2362-100 1x 100 µL
GAD2 / GAD65 (GABAergic Neuronal Marker) (GAD2/2362), 0.2mg/mL
Sign In for Pricing
View Details 
HA723442B 100 µL
Mouse Factor XII Recombinant Rabbit monoclonal Antibody
Sign In for Pricing
View Details