THR-β agonist 5
THR-β agonist 5 (compound 54) is a potent THR-β agonist, with an EC50 of [1].
Product Specifications
CAS Number
[2542029-74-1]
UNSPSC
12352005
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/thr-β-agonist-5.html
Purity
99.89
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(N1)N(C2=CC(C)=C(CC3=CC=C(NC=C4C(C)C)C4=N3)C(C)=C2)N=CC1=O
Molecular Formula
C22H23N5O2
Molecular Weight
389.45
References & Citations
[1]Koen Vandyck, et al. MODULATORS OF THR-β AND METHODS OF USE THEREOF. WO2020227549A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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