Namodenoson
Namodenoson (CF-102) is a selective A3 adenosine receptor (A3AR) agonist (Ki=0.33 nM) . Namodenoson displays 2500- and 1400-fold selectivity over A1 and A2A receptors respectively[1][2].
Product Specifications
CAS Number
163042-96-4
Product Name Alternative
CF-102; 2-Cl-IB-MECA
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-Cl-IB-MECA.html
Purity
99.56
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=NC(NCC2=CC=CC(I)=C2)=C3N=CN([C@@H]4O[C@H](C(NC)=O)[C@@H](O)[C@H]4O)C3=N1
Molecular Formula
C18H18ClIN6O4
Molecular Weight
544.73
Precautions
H302, H315, H319, H335
References & Citations
[1]Van Schaick EA et al. Hemodynamic effects and histamine release elicited by the selective adenosine A3 receptor agonist 2-Cl-IB-MECA in conscious rats. Eur J Pharmacol. 1996 Jul 25;308 (3) :311-4.|[2]Jacobson KA et al. Adenosine A3 receptors: novel ligands and paradoxical effects. Trends Pharmacol Sci. 1998 May;19 (5) :184-91.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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