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Namodenoson

Namodenoson (CF-102) is a selective A3 adenosine receptor (A3AR) agonist (Ki=0.33 nM) . Namodenoson displays 2500- and 1400-fold selectivity over A1 and A2A receptors respectively[1][2].

Product Specifications

CAS Number

163042-96-4

Product Name Alternative

CF-102; 2-Cl-IB-MECA

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2-Cl-IB-MECA.html

Purity

99.56

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClC1=NC(NCC2=CC=CC(I)=C2)=C3N=CN([C@@H]4O[C@H](C(NC)=O)[C@@H](O)[C@H]4O)C3=N1

Molecular Formula

C18H18ClIN6O4

Molecular Weight

544.73

Precautions

H302, H315, H319, H335

References & Citations

[1]Van Schaick EA et al. Hemodynamic effects and histamine release elicited by the selective adenosine A3 receptor agonist 2-Cl-IB-MECA in conscious rats. Eur J Pharmacol. 1996 Jul 25;308 (3) :311-4.|[2]Jacobson KA et al. Adenosine A3 receptors: novel ligands and paradoxical effects. Trends Pharmacol Sci. 1998 May;19 (5) :184-91.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 3

Available Sizes

Frequently Asked Questions

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