Blebbistatin
Product Specifications
UNSPSC Description
Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor, promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing, and better preserves cell junctional integrity and barrier function. Blebbistatin blocks cell migration[1][2].
Target Antigen
Myosin
Type
Reference compound
Related Pathways
Cytoskeleton
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/blebbistatin.html
Smiles
O=C1C2(O)C(N(C3=CC=CC=C3)CC2)=NC4=C1C=C(C)C=C4
Molecular Weight
292.338
References & Citations
[1]Ho WT, et al. Targeting non-muscle myosin II promotes corneal endothelial migration through regulating lamellipodial dynamics. J Mol Med (Berl). 2019 Sep;97(9):1345-1357.|[2]Liang Ma, et al. Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration. Cell Res. 2015 Jan;25(1):24-38.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-13813/Blebbistatin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-13813/Blebbistatin-SDS-MedChemExpress.pdf
CAS Number
674289-55-5
Available Sizes
Curated Selection
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