Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

TBHQ (Standard)

TBHQ (Standard) is the analytical standard of TBHQ. This product is intended for research and analytical applications. TBHQ (tert-Butylhydroquinone) is a widely used Nrf2 activator, protects against Doxorubicin (DOX) -induced cardiotoxicity through activation of Nrf2[1]. TBHQ (tert-Butylhydroquinone) is also an ERK activator; rescues Dehydrocorydaline (DHC) -induced cell proliferation inhibitionin melanoma[2].

Product Specifications

CAS Number

1948-33-0

Product Name Alternative

Tert-Butylhydroquinone (Standard)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Autophagy; ERK; Ferroptosis; Keap1-Nrf2; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; Autophagy; MAPK/ERK Pathway; NF-κB; Others; Stem Cell/Wnt

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tbhq-standard.html

Purity

99.86

Solubility

DMSO : ≥ 56.66 mg/mL

Smiles

OC1=CC=C(O)C=C1C(C)(C)C

Molecular Formula

C10H14O2

Molecular Weight

166.22

Precautions

H302, H315, H319, H335

References & Citations

[1]Lin-Feng Wang, et al. Tert-butylhydroquinone ameliorates doxorubicin-induced cardiotoxicity by activating Nrf2 and inducing the expression of its target genes. Am J Transl Res. 2015; 7 (10) : 1724–1735.|[2]Hu H, et al. Dehydrocorydaline inhibits cell proliferation, migration and invasion via suppressing MEK1/2-ERK1/2 cascade in melanoma.Onco Targets Ther. 2019 Jul 2;12:5163-5175.|[3]XIAOJING SHI, et al. Tert-butylhydroquinone attenuates the ethanol-induced apoptosis of and activates the Nrf2 antioxidant defense pathway in H9c2 cardiomyocytes.Int J Mol Med. 2016 Jul; 38 (1) : 123–130.|[4]Sukumari-Ramesh S, et al. Post-Injury Administration of Tert-butylhydroquinone Attenuates Acute Neurological Injury AfterIntracerebral Hemorrhage in Mice.J Mol Neurosci. 2016 Apr;58 (4) :525-31.

Shipping Conditions

Room Temperature

Storage Conditions

4°C, sealed storage, away from light and moisture

Scientific Category

Reference Standards

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

FOXA1 / HNF3A (FOXA1/2230R), 0.2mg/mL
BNUB2230-500 1x 500 µL

FOXA1 / HNF3A (FOXA1/2230R), 0.2mg/mL

Sign In for Pricing
View Details
Human CHMP4A activation kit by CRISPRa
GA109218 1 Kit

Human CHMP4A activation kit by CRISPRa

Sign In for Pricing
View Details
TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), CF647 conjugate, 0.1mg/mL
BNC472052-500 1x 500 µL

TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
5, 5'-Dimethyl BAPTA, tetrapotassium salt
#50008 1x 100 mg

5, 5'-Dimethyl BAPTA, tetrapotassium salt

Sign In for Pricing
View Details
Human CT47A7 activation kit by CRISPRa
GA118834 1 Kit

Human CT47A7 activation kit by CRISPRa

Sign In for Pricing
View Details
SEPTIN4 (33-44) Goat Polyclonal Antibody
AP22420PU-N 100 µg

SEPTIN4 (33-44) Goat Polyclonal Antibody

Sign In for Pricing
View Details