TY-52156
TY-52156 is a potent and selective S1P3 receptor antagonist with a Ki value of 110 nM[1].
Product Specifications
CAS Number
[934369-14-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/TY-52156.html
Concentration
10mM
Purity
99.42
Solubility
DMSO : ≥ 100 mg/mL
Smiles
ClC1=CC=C(/N=C(NNC2=CC=C(Cl)C=C2)/C(C(C)(C)C)=O)C=C1
Molecular Formula
C18H19Cl2N3O
Molecular Weight
364.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Murakami A, et al. Sphingosine 1-phosphate (S1P) regulates vascular contraction via S1P3 receptor: investigation based on a new S1P3 receptor antagonist. Mol Pharmacol. 2010 Apr;77 (4) :704-13.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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