Octopamine (hydrochloride)

Octopamine ((±) -p-Octopamine) hydrochloride, a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. Octopamine hydrochloride can stimulate alpha2-adrenoceptors (ARs) in Chinese hamster ovary cells transfected with human alpha2-ARs. Octopamine hydrochloride increased glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis and the portal perfusion pressure[1][2][3].

Product Specifications

CAS Number

[770-05-8]

Product Name Alternative

(±) -p-Octopamine (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor; Endogenous Metabolite

Type

Natural Products

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Octopamine-hydrochloride.html

Purity

99.90

Solubility

DMSO : ≥ 100 mg/mL|H2O : ≥ 50 mg/mL

Smiles

OC(C1=CC=C(O)C=C1)CN.Cl

Molecular Formula

C8H12ClNO2

Molecular Weight

189.64

Precautions

H302, H315, H319, H335

References & Citations

[1]Farooqui T. Octopamine-mediated neuromodulation of insect senses. Neurochem Res. 2007;32 (9) :1511-1529.|[2]Roeder T. Octopamine in invertebrates. Prog Neurobiol. 1999;59 (5) :533-561.|[3]Axelrod J, et al. Octopamine. Nature. 1977;265 (5594) :501-504.