Glutathione oxidized

Glutathione oxidized (L-Glutathione oxidized) is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes[1][2].

Product Specifications

CAS Number

[27025-41-8]

Product Name Alternative

L-Glutathione oxidized; GSSG; Oxiglutatione

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Reactive Oxygen Species (ROS)

Type

Peptides

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Glutathione_oxidized.html

Purity

99.0

Solubility

H2O : ≥ 200 mg/mL

Smiles

O=C(NCC(O)=O)[C@H](CSSC[C@@H](C(NCC(O)=O)=O)NC(CC[C@H](N)C(O)=O)=O)NC(CC[C@H](N)C(O)=O)=O

Molecular Formula

C20H32N6O12S2

Molecular Weight

612.63

Precautions

H302, H315, H319, H335

References & Citations

[1]Nur E, et al. Increased efflux of oxidized glutathione (GSSG) causes glutathione depletion and potentially diminishes antioxidant defense in sickle erythrocytes. Biochim Biophys Acta. 2011 Nov;1812 (11) :1412-7.|[2]Downs CA, et al. Oxidized glutathione (GSSG) inhibits epithelial sodium channel activity in primary alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2015 May 1;308 (9) :L943-52.