Tricetin 3',4',5'-trimethyl ether

Tricetin 3',4',5'-trimethyl ether (5,7-Dihydroxy-3',4',5'-trimethoxyflavone) is a flavone glucoside, that can be isolated the flowers of Chrysanthemum sinensea. Tricetin 3',4',5'-trimethyl ether displays xanthine oxidase competitive-type inhibitory activity, with an IC50 of 0.51 μM and a Ki of 0.37 μM[1].

Product Specifications

CAS Number

[18103-42-9]

Product Name Alternative

5,7-Dihydroxy-3',4',5'-trimethoxyflavone

UNSPSC

12352005

Hazard Statement

H315-H319

Target

Xanthine Oxidase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/tricetin-3-4-5-trimethyl-ether.html

Solubility

10 mM in DMSO

Smiles

O=C1C=C(C2=CC(OC)=C(OC)C(OC)=C2)OC3=CC(O)=CC(O)=C13

Molecular Formula

C18H16O7

Molecular Weight

344.32

Precautions

P264-P280-P302+P352-P362+P364

References & Citations

[1]Nguyen MT, Awale S, Tezuka Y, Ueda JY, Tran Ql, Kadota S. Xanthine oxidase inhibitors from the flowers of Chrysanthemum sinense. Planta Med. 2006 Jan;72 (1) :46-51.