HTYR/AbTYR-IN-1
HTYR/AbTYR-IN-1 (Compound 7) is a hTYR/AbTYR dual inhibitor, with IC50s of 5.4 μM and 3.52 μM for hTYR and AbTYR respectively[1].
Product Specifications
CAS Number
[1625821-37-5]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Tyrosinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/htyr-abtyr-in-1.html
Purity
99.06
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
COC1=CC=CC=C1C(N2CCN(C3=CC=C(O)C=C3)CC2)=O
Molecular Formula
C18H20N2O3
Molecular Weight
312.36
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Ricci F, et al. Computational methods to analyze and predict the binding mode of inhibitors targeting both human and mushroom tyrosinase. Eur J Med Chem. 2023 Aug 28;260:115771.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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