Human APP ELISA Kit

Detect Range: 312 pg/mL-20 000 pg/mL. Sensitivity: 100 pg/mL. Gene_name: APP. Gene_full_name: Amyloid beta A4 protein. Protein_name: Amyloid beta A4 protein. Sample Type: cell culture supernates cell lysates tissue homogenates serum and plasma (heparin EDTA) . Tmb_incubation: 15-20 min. Capture_antibody: monoclonal antibody from mouse. Detection_antibody: polyclonal antibody from goat. Research_category: cell biology|apoptosis|intracellular|associated proteins|neuroscience|neurology process|neural signal transduction|adapters|cytoplasmic|protein trafficking|organelle proteins|neurogenesis|developmental biology|organogenesis|nervous system development. Sequence_similarities: Belongs to the APP family. Tissue_specificity: Expressed in all fetal tissues examined withhighest levels in brain kidney heart and spleen. Weak expressionin liver. In adult brain highest expression found in the frontallobe of the cortex and in the anterior perisylvian cortex-opercular gyri. Moderate expression in the cerebellar cortex theposterior perisylvian cortex-opercular gyri and the temporalassociated cortex. Weak expression found in the striate extra-striate and motor cortices. Expressed in cerebrospinal fluid andplasma. Isoform APP695 is the predominant form in neuronal tissue isoform APP751 and isoform APP770 are widely expressed in non-neuronal cells. Isoform APP751 is the most abundant form in T-lymphocytes. Appican is expressed in astrocytes.