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Suciraslimab

Suciraslimab (SM03) is an anti-human CD22 monoclonal antibody. Suciraslimab inhibits NLRP3 and ASC signaling. Suciraslimab suppresses cytokine (IL-1β, IL-12, IL-23) secretion and α4 integrin expression. Suciraslimab improves working memory and neuroinflammation[1]. Suciraslimab isotype control product: Human IgG1 kappa, Isotype Control (HY-P99001) .

Product Specifications

CAS Number

[2415439-63-1]

Product Name Alternative

SM03

UNSPSC

12352203

Target

CD22; Integrin; Interleukin Related; NOD-like Receptor (NLR)

Type

Inhibitory Antibodies

Related Pathways

Cytoskeleton; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/suciraslimab.html

Purity

97.42

Smiles

[Suciraslimab]

Molecular Weight

(146.16 kDa)

References & Citations

[1]Mai YD, et al. CD22 modulation alleviates amyloid β-induced neuroinflammation. J Neuroinflammation. 2025 Feb 5;22 (1) :32.

Shipping Conditions

Dry Ice

Storage Conditions

-80°C

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 3

Isoform

IL-1; IL-12; IL-23

Available Sizes

Curated Selection

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