Wikstrol A
Wikstrol A is a potent antifungal, antimitotic and anti-HIV-1 Agent. Wikstrol A induces morphological deformation of P. oryzae mycelia with an MMDC value of 70.1 µM. Wikstrol A shows activity against microtubule polymerization with an IC50 value of 131 µM. Wikstrol A shows anti-HIV-1 activity with an IC50 value of 67.8 µM[1].
Product Specifications
CAS Number
[159736-35-3]
UNSPSC
12352005
Target
Fungal; HIV; Microtubule/Tubulin
Type
Natural Products
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Cytoskeleton
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/wikstrol-a.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C([C@H]2OC3=C(C4=C(C5=CC=C(O)C=C5)OC(C=C(C=C6O)O)=C6C4=O)C(O)=CC(O)=C3C[C@@H]2O)C=C1
Molecular Formula
C30H22O10
Molecular Weight
542.49
References & Citations
[1]Hu K, et al. Antifungal, antimitotic and anti-HIV-1 agents from the roots of Wikstroemia indica. Planta Med. 2000 Aug;66 (6) :564-7.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
HIV-1
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