Meloxicam-d3

Meloxicam-d3 is deuterium labeled Meloxicam. Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity, with IC50s of 0.49 μM and 36.6 μM for COX-2 and COX-1, respectively[1].

Product Specifications

CAS Number

[942047-63-4]

UNSPSC

12352005

Hazard Statement

H301

Target

Apoptosis; Autophagy; COX

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Autophagy; Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer; Inflammation/Immunology

Purity

99.55

Solubility

10 mM in DMSO|DMF : ≥ 20mg/mL|DMSO : ≥ 20mg/mL

Smiles

O=C(C1=C(O)C2=CC=CC=C2S(N1C([2H])([2H])[2H])(=O)=O)NC3=NC=C(C)S3

Molecular Formula

C14H10D3N3O4S2

Molecular Weight

354.42

Precautions

H301

References & Citations

[1]Lazer ES, et al. Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity. J Med Chem. 1997 Mar 14;40 (6) :980-9.