Hepsulfam
Hepsulfam (NCI 329680; ZINC01574758) is a anticancer agent that shows excellent antileukemic activity with an median IC50 of 0.91 μg/mL in a panel of different tumors.
Product Specifications
CAS Number
96892-57-8
Product Name Alternative
NCI 329680; ZINC01574758
UNSPSC
12352211
Target
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Hepsulfam.html
Concentration
10mM
Purity
99.31
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(OCCCCCCCOS(=O)(N)=O)(N)=O
Molecular Formula
C7H18N2O6S2
Molecular Weight
290.36
References & Citations
[1]Berger DP, et al. Preclinical activity of hepsulfam and busulfan in solid human tumor xenografts and human bone marrow. Anticancer Drugs. 1992 Oct;3 (5) :531-9.|[2]Pacheco DY, et al. Mechanisms of toxicity of hepsulfam in human tumor cell lines. Cancer Res. 1990 Dec 1;50 (23) :7555-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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