5- (Hydroxymethyl) -2′,3′-O- (1-methylethylidene) uridine

5- (Hydroxymethyl) -2′,3′-O- (1-methylethylidene) uridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

Product Specifications

CAS Number

[3816-77-1]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/5-hydroxymethyl-2-3-o-1-methylethylidene-uridine.html

Solubility

10 mM in DMSO

Smiles

OC[C@@H]1[C@@H](OC(C)(C)O2)[C@@H]2[C@H](N3C=C(CO)C(NC3=O)=O)O1

Molecular Formula

C13H18N2O7

Molecular Weight

314.29

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

References & Citations

[1]Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16 (9) :7980-93.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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