ML335

ML335 is a selective activator of both TREK-1 and TREK-2.

Product Specifications

CAS Number

[825658-06-8]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ML335.html

Purity

99.73

Solubility

DMSO : 155 mg/mL (ultrasonic; warming)

Smiles

O=C(NCC1=CC=C(Cl)C=C1Cl)C2=CC=C(NS(=O)(C)=O)C=C2

Molecular Formula

C15H14Cl2N2O3S

Molecular Weight

373.25

Precautions

H315, H319, H335

References & Citations

[1]Lolicato M, et al. K2P2.1 (TREK-1) -activator complexes reveal a cryptic selectivity filter binding site. Nature. 2017 Jul 20;547 (7663) :364-368.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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