ML335
ML335 is a selective activator of both TREK-1 and TREK-2.
Product Specifications
CAS Number
[825658-06-8]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ML335.html
Purity
99.73
Solubility
DMSO : 155 mg/mL (ultrasonic; warming)
Smiles
O=C(NCC1=CC=C(Cl)C=C1Cl)C2=CC=C(NS(=O)(C)=O)C=C2
Molecular Formula
C15H14Cl2N2O3S
Molecular Weight
373.25
Precautions
H315, H319, H335
References & Citations
[1]Lolicato M, et al. K2P2.1 (TREK-1) -activator complexes reveal a cryptic selectivity filter binding site. Nature. 2017 Jul 20;547 (7663) :364-368.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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