LRP-6, Human (HEK293, mFc)

LRP-6 protein is a key component of the Wnt-Fzd-LRP5-LRP6 complex, a component of β-catenin signaling, and is essential for bone formation. LRP-6 acts as a cell surface co-receptor and coordinates the formation of signalosomes by clustering receptor-ligand complexes. LRP-6 Protein, Human (HEK293, mFc) is the recombinant human-derived LRP-6 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of LRP-6 Protein, Human (HEK293, mFc) is 611 a.a., with molecular weight of 100-120 kDa.

APLLLYANRR DLRLVDATNG KENATIVVGG LEDAAAVDFV FSHGLIYWSD VSEEAIKRTE FNKTESVQNV VVSGLLSPDG LACDWLGEKL YWTDSETNRI EVSNLDGSLR KVLFWQELDQ PRAIALDPSS GFMYWTDWGE VPKIERAGMD GSSRFIIINS EIYWPNGLTL DYEEQKLYWA DAKLNFIHKS NLDGTNRQAV VKGSLPHPFA LTLFEDILYW TDWSTHSILA CNKYTGEGLR EIHSDIFSPM DIHAFSQQRQ PNATNPCGID NGGCSHLCLM SPVKPFYQCA CPTGVKLLEN GKTCKDGATE LLLLARRTDL RRISLDTPDF TDIVLQLEDI RHAIAIDYDP VEGYIYWTDD EVRAIRRSFI DGSGSQFVVT AQIAHPDGIA VDWVARNLYW TDTGTDRIEV TRLNGTMRKI LISEDLEEPR AIVLDPMVGY MYWTDWGEIP KIERAALDGS DRVVLVNTSL GWPNGLALDY DEGKIYWGDA KTDKIEVMNT DGTGRRVLVE DKIPHIFGFT LLGDYVYWTD WQRRSIERVH KRSAEREVII DQLPDLMGLK ATNVHRVIGS NPCAEENGGC SHLCLYRPQG LRCACPIGFE LISDMKTCIV P