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Ebio1

Ebio1 is a selective voltage-gated potassium channel KCNQ2 activator. Ebio1 activates KCNQ2 by generating an extended channel gate with greater conductance at a saturation voltage (+50 mV) [1].

Product Specifications

CAS Number

339287-36-4

UNSPSC

12352005

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ebio1.html

Purity

99.99

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(C=C1)F)NC2=CC=C3CCC4=CC=CC2=C43

Molecular Formula

C19H14FNO

Molecular Weight

291.32

References & Citations

[1]Zhang S, Ma D, Wang K, et al. A small-molecule activation mechanism that directly opens the KCNQ2 channel[J]. Nature Chemical Biology, 2024: 1-10.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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