Ebio1
Ebio1 is a selective voltage-gated potassium channel KCNQ2 activator. Ebio1 activates KCNQ2 by generating an extended channel gate with greater conductance at a saturation voltage (+50 mV) [1].
Product Specifications
CAS Number
339287-36-4
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ebio1.html
Purity
99.99
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(C=C1)F)NC2=CC=C3CCC4=CC=CC2=C43
Molecular Formula
C19H14FNO
Molecular Weight
291.32
References & Citations
[1]Zhang S, Ma D, Wang K, et al. A small-molecule activation mechanism that directly opens the KCNQ2 channel[J]. Nature Chemical Biology, 2024: 1-10.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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