TEPC466
TEPC466 is a novel TEPP-46-based aggregation-induced emission (AIE) probe. TEPC466 shows a high degree of selectivity and sensitivity for the detection of PKM2 protein via the AIE effect. EPC466 can be used for the detection of PKM2. TEPC466 is successfully applied in imaging the PKM2 protein in colorectal cancer cells with low toxicity. TEPC466 is a useful tool for cancer diagnosis and research[1].
Product Specifications
CAS Number
2621957-88-6
UNSPSC
12171500
Target
Pyruvate Kinase
Type
Dye Reagents
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tepc466.html
Purity
99.92
Solubility
10 mM in DMSO
Smiles
O=C1N(N=CC2=C1N(C)C3=C2SC(S(C)=O)=C3)CC4=CC=CC(NC(C5=CC6=CC=CC=C6OC5=O)=O)=C4
Molecular Formula
C27H20N4O5S2
Molecular Weight
544.60
References & Citations
[1]Wang D, et al. TEPP-46-Based AIE Fluorescent Probe for Detection and Bioimaging of PKM2 in Living Cells. Anal Chem. 2021;93 (37) :12682-12689.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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