Yohimbic acid

Yohimbic acid is an amphoteric demethylated derivative of Yohimbine. Yohimbic acid exhibits vasodilatory action. Yohimbic acid also can be used for the research of osteoarthritis (OA) [1][2][3].

Product Specifications

CAS Number

[522-87-2]

UNSPSC

12352005

Hazard Statement

H301, H311, H331

Target

Drug Derivative

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/yohimbic-acid.html

Purity

99.09

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC([C@@H]1[C@@]2([H])C[C@@]3([H])C4=C(CCN3C[C@]2([H])CC[C@@H]1O)C5=CC=CC=C5N4)=O

Molecular Formula

C20H24N2O3

Molecular Weight

340.42

Precautions

H301, H311, H331

References & Citations

[1]Wang S, et, al. Significantly dysregulated genes in osteoarthritic labrum cells identified through gene expression profiling. Mol Med Rep. 2019 Aug; 20 (2) : 1716-1724.|[2]HAMET R. [Sympatholytic activity and toxicity of an amphoteric demethylated derivative of yohimbine: yohimbic acid]. C R Hebd Seances Acad Sci. 1951 Oct 29;233 (18) :1069-71.|[3]HAMET R. [Demonstration of the direct vasodilatory action of yohimbic acid and Py-tetrahydroquinoline]. C R Hebd Seances Acad Sci. 1960 Jun 27;250:4473-5.