Yohimbic acid
Yohimbic acid is an amphoteric demethylated derivative of Yohimbine. Yohimbic acid exhibits vasodilatory action. Yohimbic acid also can be used for the research of osteoarthritis (OA) [1][2][3].
Product Specifications
CAS Number
[522-87-2]
UNSPSC
12352005
Hazard Statement
H301, H311, H331
Target
Drug Derivative
Type
Natural Products
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/yohimbic-acid.html
Purity
99.09
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC([C@@H]1[C@@]2([H])C[C@@]3([H])C4=C(CCN3C[C@]2([H])CC[C@@H]1O)C5=CC=CC=C5N4)=O
Molecular Formula
C20H24N2O3
Molecular Weight
340.42
Precautions
H301, H311, H331
References & Citations
[1]Wang S, et, al. Significantly dysregulated genes in osteoarthritic labrum cells identified through gene expression profiling. Mol Med Rep. 2019 Aug; 20 (2) : 1716-1724.|[2]HAMET R. [Sympatholytic activity and toxicity of an amphoteric demethylated derivative of yohimbine: yohimbic acid]. C R Hebd Seances Acad Sci. 1951 Oct 29;233 (18) :1069-71.|[3]HAMET R. [Demonstration of the direct vasodilatory action of yohimbic acid and Py-tetrahydroquinoline]. C R Hebd Seances Acad Sci. 1960 Jun 27;250:4473-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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