Eflornithine (hydrochloride hydrate) (Standard)

Eflornithine (hydrochloride hydrate) (Standard) is the analytical standard of Eflornithine (hydrochloride hydrate) . This product is intended for research and analytical applications. Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women[1].

Product Specifications

CAS Number

[96020-91-6]

Product Name Alternative

DFMO hydrochloride hydrate (Standard) ; MDL-71782 hydrochloride hydrate (Standard) ; RMI-71782 hydrochloride hydrate (Standard) ; α-difluoromethylornithine hydrochloride hydrate (Standard)

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Parasite; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/eflornithine-hydrochloride-hydrate-standard.html

Purity

99.94

Smiles

NC(CCCN)(C(F)F)C(O)=O.[H]Cl.O

Molecular Formula

C6H15ClF2N2O3

Molecular Weight

236.64

Precautions

H302, H315, H319, H335

References & Citations

[1]Burri C, et al. Eflornithine for the treatment of human African trypanosomiasis. Parasitol Res. 2003 Jun;90 Supp 1:S49-52.|[2]Balfour JA, et al. Topical eflornithine. Am J Clin Dermatol. 2001;2 (3) :197-201; discussion 202.|[3]Kumar A, et al. A method to improve the efficacy of topical eflornithine hydrochloride cream. Drug Deliv. 2016 Jun;23 (5) :1495-501.|[4]Lipke DW, et al. Eflornithine alters changes in vascular responsiveness associated with coarctation hypertension. Clin Exp Hypertens. 1997 Apr;19 (3) :297-312.