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NF-κB-IN-17

NF-κB-IN-17 (Zinc5) is a NF-κB inhibitor. NF-κB-IN-17 inhibits TNF-α-induced NF-κB DNA binding activity in C2C12 cells[1].

Product Specifications

CAS Number

786721-94-6

UNSPSC

12352005

Target

NF-κB

Type

Reference compound

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/nf-κb-in-17.html

Smiles

O=C(CC1=CC=CC=C1F)OCC(NC2=NC=C(C=C2)Cl)=O

Molecular Formula

C15H12ClFN2O3

Molecular Weight

322.72

References & Citations

[1]Zhao J, et al. Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation. PLoS Biol. 2018 Jun 11;16 (6) :e2004663.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Frequently Asked Questions

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