Sodium Channel inhibitor 1
Sodium Channel inhibitor1, one of 3-Oxoisoindoline-1-carboxamides, is a novel and selective voltage-gated sodium channel for pain treatment. IC50 Value: 0.16 uM (Na v1.7, V hold-90mV) ; 0.41 uM (Na v1.7, V hold-90mV) [1] Target: Na v1.7 Sodium Channel inhibitor1 demonstrated concentration-dependent efficacy in preclinical behavioral pain models.
Product Specifications
CAS Number
[1198117-23-5]
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sodium-channel-inhibitor-1.html
Purity
99.38
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1N(CCC2=NC=CC=C2)C(C3=C1C(F)=CC=C3)=O)NCC4=CC=C(OC(F)(F)F)C=C4
Molecular Formula
C24H19F4N3O3
Molecular Weight
473.42
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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