A 410099.1, amine-Boc (hydrochloride)
A 410099.1, amine-Boc hydrochloride is a functionalized IAP ligand and can be used for the synthesis of PROTACs, such as PROTACs targeting BTK (PROTACs 4 and 5) [1].
Product Specifications
CAS Number
2374122-37-7
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/a-410099-1-amine-boc-hydrochloride.html
Purity
99.71
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N(C[C@H]1N)[C@@H](C1)C(N[C@H]2C3=CC=CC=C3CCC2)=O)[C@H](C4CCCCC4)NC([C@H](C)N(C)C(OC(C)(C)C)=O)=O.Cl
Molecular Formula
C32H50ClN5O5
Molecular Weight
620.22
Precautions
H315, H319, H320
References & Citations
[1]Christopher P Tinworth, et al. PROTAC-Mediated Degradation of Bruton's Tyrosine Kinase Is Inhibited by Covalent Binding. ACS Chem Biol.2019 Mar 15;14 (3) :342-347
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CIAP1
Available Sizes
Frequently Asked Questions
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