(S) -Dolaphenine (hydrochloride)
(S) -Dolaphenine hydrochloride is a component of Dolastatin 10 (HY-15580) . Dolastatin 10, an antineoplastic agent, inhibits tubulin polymerization[1].
Product Specifications
CAS Number
[135383-60-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Others; Cancer
Assay Protocol
https://www.medchemexpress.com/_S_-Dolaphenine-hydrochloride.html
Purity
98.54
Solubility
DMSO : ≥ 50 mg/mL|H2O : ≥ 50 mg/mL
Smiles
N[C@H](C1=NC=CS1)CC2=CC=CC=C2.Cl
Molecular Formula
C11H13ClN2S
Molecular Weight
240.75
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhou W , et al. A practical approach to asymmetric synthesis of dolastatin 10. Org Biomol Chem. 2017;15 (29) :6119-6131.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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